Structural basis of inhibition of a transporter from Staphylococcus aureus, NorC, through a single-domain camelid antibody

Transporters play vital roles in acquiring antimicrobial resistance among pathogenic bacteria. In this study, we report the X-ray structure of NorC, a 14-transmembrane major facilitator superfamily member that is implicated in fluoroquinolone resistance in drug-resistant Staphylococcus aureus strain...

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Detalles Bibliográficos
Autores principales: Kumar, Sushant, Athreya, Arunabh, Gulati, Ashutosh, Nair, Rahul Mony, Mahendran, Ithayaraja, Ranjan, Rakesh, Penmatsa, Aravind
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8257674/
https://www.ncbi.nlm.nih.gov/pubmed/34226658
http://dx.doi.org/10.1038/s42003-021-02357-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8257674/
https://www.ncbi.nlm.nih.gov/pubmed/34226658
http://dx.doi.org/10.1038/s42003-021-02357-x

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