Cargando…

Structural basis of inhibition of a transporter from Staphylococcus aureus, NorC, through a single-domain camelid antibody

Transporters play vital roles in acquiring antimicrobial resistance among pathogenic bacteria. In this study, we report the X-ray structure of NorC, a 14-transmembrane major facilitator superfamily member that is implicated in fluoroquinolone resistance in drug-resistant Staphylococcus aureus strain...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kumar, Sushant, Athreya, Arunabh, Gulati, Ashutosh, Nair, Rahul Mony, Mahendran, Ithayaraja, Ranjan, Rakesh, Penmatsa, Aravind
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8257674/ https://www.ncbi.nlm.nih.gov/pubmed/34226658 http://dx.doi.org/10.1038/s42003-021-02357-x

Ejemplares similares

Cryo‐EM structure of antibacterial efflux transporter QacA from Staphylococcus aureus reveals a novel extracellular loop with allosteric role
por: Majumder, Puja, et al.
Publicado: (2023)

Cryo-EM structure of GABA transporter 1 reveals substrate recognition and transport mechanism
por: Nayak, Smruti Ranjan, et al.
Publicado: (2023)

Structural basis for inhibition of the drug efflux pump NorA from Staphylococcus aureus
por: Brawley, Douglas N., et al.
Publicado: (2022)

Bridging theory and practice: design and implementation of the NORC-SSP linkage evaluation
por: Kyriacou, Corinne
Publicado: (2009)

NoRCE: non-coding RNA sets cis enrichment tool
por: Olgun, Gulden, et al.
Publicado: (2021)

Molecular Basis of Histone Tail Recognition by Human TIP5 PHD Finger and Bromodomain of the Chromatin Remodeling Complex NoRC
por: Tallant, Cynthia, et al.
Publicado: (2015)

Correction to: NoRCE: non‑coding RNA sets cis enrichment tool
por: Olgun, Gulden, et al.
Publicado: (2021)

Structural Basis for Potent Neutralization of Betacoronaviruses by Single-Domain Camelid Antibodies
por: Wrapp, Daniel, et al.
Publicado: (2020)

Structural Basis for Potent Neutralization of Betacoronaviruses by Single-Domain Camelid Antibodies
por: Wrapp, Daniel, et al.
Publicado: (2020)

Camelid Vaccinations
por: Long, Patrick O.
Publicado: (2014)

Camelids Are Not Ruminants
por: Fowler, Murray E.
Publicado: (2008)

Structural basis of norepinephrine recognition and transport inhibition in neurotransmitter transporters
por: Pidathala, Shabareesh, et al.
Publicado: (2021)

A Scoping Review of Innovative Housing for Older Adults: Focus on Homesharing, Cohousing, NORC-SSPs, and Villages
por: Seetharaman, Kishore, et al.
Publicado: (2020)

Infectious diseases in camelids /
por: Wernery, Ulrich
Publicado: (2002)

Methane Emission by Camelids
por: Dittmann, Marie T., et al.
Publicado: (2014)

Reproductive emergencies in camelids
por: Tibary, A., et al.
Publicado: (2008)

Camelid Herd Health
por: Jones, Meredyth, et al.
Publicado: (2009)

Modulation of Drug Resistance by Furanochromones in NorA Overexpressing Staphylococcus Aureus
por: Rodrigues, Damara F., et al.
Publicado: (2022)

Structural basis for action by diverse antidepressants on biogenic amine transporters
por: Wang, Hui, et al.
Publicado: (2013)

Resveratrol as an Inhibitor of the NorA Efflux Pump and Resistance Modulator in Staphylococcus aureus
por: Santos, Madalena, et al.
Publicado: (2023)

Cerebrospinal Nematodiasis in 20 Camelids
por: Bertin, F.R., et al.
Publicado: (2016)

Emerging Infectious Diseases in Camelids
por: Khalafalla, Abdelmalik I.
Publicado: (2016)

Structural Basis for the Specific Neutralization of Stx2a with a Camelid Single Domain Antibody Fragment
por: Bernedo-Navarro, Robert Alvin, et al.
Publicado: (2018)

Enteric Viral Infections among Domesticated South American Camelids: First Detection of Mammalian Orthoreovirus in Camelids
por: Castilla, Dayana, et al.
Publicado: (2021)

Genetic Diversity of norA, Coding for a Main Efflux Pump of Staphylococcus aureus
por: Costa, Sofia Santos, et al.
Publicado: (2019)

Chromatin Targeting Signals, Nucleosome Positioning Mechanism and Non-Coding RNA-Mediated Regulation of the Chromatin Remodeling Complex NoRC
por: Manelyte, Laura, et al.
Publicado: (2014)

Controlled reproduction in horses, deer, and camelids /
por: Gordon, Ian R.
Publicado: (1997)

Infectious causes of reproductive loss in camelids
por: Tibary, A., et al.
Publicado: (2006)

Viral Diseases of New World Camelids
por: Kapil, Sanjay, et al.
Publicado: (2009)

Editorial: Reproduction in South American Camelids
por: Ratto, Marcelo, et al.
Publicado: (2021)

Early embryonic death in equines and camelids
por: Ashraf, Rehan, et al.
Publicado: (2022)

Inhibition of Staphylococcus pseudintermedius Efflux Pumps by Using Staphylococcus aureus NorA Efflux Pump Inhibitors
por: Rampacci, Elisa, et al.
Publicado: (2023)

A new model of care collaboration for community-dwelling elders: findings and lessons learned from the NORC-Health Care linkage evaluation
por: Kyriacou, Corinne, et al.
Publicado: (2011)

A new model of care collaboration for community-dwelling elders: findings and lessons learned from the NORC-health care linkage evaluation
por: Kyriacou, Corinne
Publicado: (2009)

Promising Aging in Community Models in the U.S.: Village, Naturally Occurring Retirement Community (NORC), Cohousing, and University-Based Retirement Community (UBRC)
por: Hou, Su-I, et al.
Publicado: (2021)

Biomechanical analysis of the camelid cervical intervertebral disc
por: Stolworthy, Dean K., et al.
Publicado: (2014)

Atrial Fibrillation in Eight New World Camelids
por: Bozorgmanesh, R., et al.
Publicado: (2016)

South American Camelids: their values and contributions to people
por: Vilá, Bibiana, et al.
Publicado: (2020)

A review of coccidiosis in South American camelids
por: Dubey, J. P.
Publicado: (2018)

Differential Effects of Estradiol on Reproductive Function in Camelids
por: Carrasco, Rodrigo A., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_16db0ddk6p9s1t90alfroll347