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MiR-146a regulates regulatory T cells to suppress heart transplant rejection in mice

Regulatory T cells (Tregs), which characteristically express forkhead box protein 3 (Foxp3), are essential for the induction of immune tolerance. Here, we investigated microRNA-146a (miR-146a), a miRNA that is widely expressed in Tregs and closely related to their homeostasis and function, with the...

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Detalles Bibliográficos
Autores principales: Lu, Jian, Wang, Weiwei, Li, Peiyuan, Wang, Xiaodong, Gao, Chao, Zhang, Baotong, Du, Xuezhi, Liu, Yanhong, Yang, Yong, Qi, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8257678/
https://www.ncbi.nlm.nih.gov/pubmed/34226512
http://dx.doi.org/10.1038/s41420-021-00534-9