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An in situ activity assay for lysyl oxidases

The lysyl oxidase family of enzymes (LOXs) catalyze oxidative deamination of lysine side chains on collagen and elastin to initialize cross-linking that is essential for the formation of the extracellular matrix (ECM). Elevated expression of LOXs is highly associated with diverse disease processes....

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Detalles Bibliográficos
Autores principales: Wang, Huilei, Poe, Alan, Pak, Lydia, Nandakumar, Kavitha, Jandu, Sandeep, Steppan, Jochen, Löser, Reik, Santhanam, Lakshmi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8257687/
https://www.ncbi.nlm.nih.gov/pubmed/34226627
http://dx.doi.org/10.1038/s42003-021-02354-0