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m6A modification promotes miR-133a repression during cardiac development and hypertrophy via IGF2BP2

Both N6-methyladenosine (m6A) RNA modification and microRNAs (miRNAs) are common regulatory mechanisms for gene post-transcription by modulating mRNA stability and translation. They also share the same 3′-untranslated regions (UTRs) regions for their target gene. However, little is known about their...

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Detalles Bibliográficos
Autores principales: Qian, Benheng, Wang, Ping, Zhang, Donghong, Wu, Lianpin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8257704/
https://www.ncbi.nlm.nih.gov/pubmed/34226535
http://dx.doi.org/10.1038/s41420-021-00552-7