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Targeting androgen receptor (AR) with antiandrogen Enzalutamide increases prostate cancer cell invasion yet decreases bladder cancer cell invasion via differentially altering the AR/circRNA-ARC1/miR-125b-2-3p or miR-4736/PPARγ/MMP-9 signals

Androgen-deprivation therapy (ADT) via targeting androgens/androgen receptor (AR) signals may suppress cell proliferation in both prostate cancer (PCa) and bladder cancer (BCa), yet its impact on the cell invasion of these two urological cancers remains unclear. Here we found targeting androgens/AR...

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Detalles Bibliográficos
Autores principales: Deng, Gang, Wang, Ronghao, Sun, Yin, Huang, Chi-Ping, Yeh, Shuyuan, You, Bosen, Feng, Changyong, Li, Gonghui, Ma, Shenglin, Chang, Chawnshang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8257744/
https://www.ncbi.nlm.nih.gov/pubmed/34127806
http://dx.doi.org/10.1038/s41418-021-00743-w