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DHX9-dependent recruitment of BRCA1 to RNA promotes DNA end resection in homologous recombination
Double stranded DNA Breaks (DSB) that occur in highly transcribed regions of the genome are preferentially repaired by homologous recombination repair (HR). However, the mechanisms that link transcription with HR are unknown. Here we identify a critical role for DHX9, a RNA helicase involved in the...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8257769/ https://www.ncbi.nlm.nih.gov/pubmed/34226554 http://dx.doi.org/10.1038/s41467-021-24341-z |