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The Impact of Excluding Nonrandomized Studies From Systematic Reviews in Rare Diseases: “The Example of Meta-Analyses Evaluating the Efficacy and Safety of Enzyme Replacement Therapy in Patients With Mucopolysaccharidosis”

Nonrandomized studies are usually excluded from systematic reviews. This could lead to loss of a considerable amount of information on rare diseases. In this article, we explore the impact of excluding nonrandomized studies on the generalizability of meta-analyses results on mucopolysaccharidosis (M...

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Detalles Bibliográficos
Autores principales: Sampayo-Cordero, Miguel, Miguel-Huguet, Bernat, Malfettone, Andrea, Pérez-García, José Manuel, Llombart-Cussac, Antonio, Cortés, Javier, Pardo, Almudena, Pérez-López, Jordi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8257960/
https://www.ncbi.nlm.nih.gov/pubmed/34239895
http://dx.doi.org/10.3389/fmolb.2021.690615