Morphine and fentanyl exposure during therapeutic hypothermia does not impair neurodevelopment

BACKGROUND: Hypothermia-treated and intubated infants with moderate or severe hypoxic-ischemic encephalopathy (HIE) usually receive morphine for sedation and analgesia (SA) during therapeutic hypothermia (TH) and endotracheal ventilation. Altered drug pharmacokinetics in this population increases th...

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Detalles Bibliográficos
Autores principales: Gundersen, Julia K, Chakkarapani, Ela, Jary, Sally, Menassa, David A, Scull-Brown, Emma, Frymoyer, Adam, Walløe, Lars, Thoresen, Marianne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8257990/
https://www.ncbi.nlm.nih.gov/pubmed/34308308
http://dx.doi.org/10.1016/j.eclinm.2021.100892

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8257990/
https://www.ncbi.nlm.nih.gov/pubmed/34308308
http://dx.doi.org/10.1016/j.eclinm.2021.100892

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