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Efficacy of minute virus of mice (MVM) inactivation utilizing high temperature short time (HTST) pasteurization and suitability assessment of pasteurized, concentrated glucose feeds in Chinese hamster ovary (CHO) cell expression systems

There is a growing need to provide effective adventitious agent mitigation for high risk upstream cell culture raw materials used for the production of biologics. It is also highly important in the growing fields of cell and gene therapies. Glucose is a critical raw material necessary for effective...

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Detalles Bibliográficos
Autores principales: Gemmell, David K., Mack, Aaron, Wegmann, Sabrina, Han, David, Tuccelli, Ronald, Johnson, Matthew, Miller, Corinne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8257999/
https://www.ncbi.nlm.nih.gov/pubmed/34257631
http://dx.doi.org/10.1002/elsc.202100044