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IL-17 Inhibits Oligodendrocyte Progenitor Cell Proliferation and Differentiation by Increasing K(+) Channel Kv1.3

Interleukin 17 (IL-17) is a signature cytokine of Th17 cells. IL-17 level is significantly increased in inflammatory conditions of the CNS, including but not limited to post-stroke and multiple sclerosis. IL-17 has been detected direct toxicity on oligodendrocyte (Ol) lineage cells and inhibition on...

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Detalles Bibliográficos
Autores principales: Liu, Han, Yang, Xueke, Yang, Jing, Yuan, Yanpeng, Wang, Yanlin, Zhang, Rui, Xiong, Huangui, Xu, Yuming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8258110/
https://www.ncbi.nlm.nih.gov/pubmed/34239419
http://dx.doi.org/10.3389/fncel.2021.679413