An in silico Framework of Cartilage Degeneration That Integrates Fibril Reorientation and Degradation Along With Altered Hydration and Fixed Charge Density Loss

Injurious mechanical loading of articular cartilage and associated lesions compromise the mechanical and structural integrity of joints and contribute to the onset and progression of cartilage degeneration leading to osteoarthritis (OA). Despite extensive in vitro and in vivo research, it remains un...

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Detalles Bibliográficos
Autores principales: Elahi, Seyed Ali, Tanska, Petri, Korhonen, Rami K., Lories, Rik, Famaey, Nele, Jonkers, Ilse
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Bioengineering and Biotechnology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8258121/
https://www.ncbi.nlm.nih.gov/pubmed/34239859
http://dx.doi.org/10.3389/fbioe.2021.680257

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8258121/
https://www.ncbi.nlm.nih.gov/pubmed/34239859
http://dx.doi.org/10.3389/fbioe.2021.680257

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