Mouse Embryonic Stem Cells Expressing GDNF Show Enhanced Dopaminergic Differentiation and Promote Behavioral Recovery After Grafting in Parkinsonian Rats

Parkinson’s disease (PD) is characterized by the progressive loss of midbrain dopaminergic neurons (DaNs) of the substantia nigra pars compacta and the decrease of dopamine in the brain. Grafting DaN differentiated from embryonic stem cells (ESCs) has been proposed as an alternative therapy for curr...

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Detalles Bibliográficos
Autores principales: Lara-Rodarte, Rolando, Cortés, Daniel, Soriano, Karla, Carmona, Francia, Rocha, Luisa, Estudillo, Enrique, López-Ornelas, Adolfo, Velasco, Iván
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8258349/
https://www.ncbi.nlm.nih.gov/pubmed/34239871
http://dx.doi.org/10.3389/fcell.2021.661656

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8258349/
https://www.ncbi.nlm.nih.gov/pubmed/34239871
http://dx.doi.org/10.3389/fcell.2021.661656

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