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Sulforaphane protects against oxidative stress-induced apoptosis via activating SIRT1 in mouse osteoarthritis

Osteoarthritis (OA), the most common form of human joint disease, is characterized by progressive degeneration of the articular cartilage, synovitis and subchondral osteoporosis. Chondrocyte apoptosis is the primary pathogenic mechanism of OA and is considered to be a potential therapeutic target. S...

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Detalles Bibliográficos
Autores principales: Chen, Mangmang, Huang, Lipeng, Lv, Yangxun, Li, Liubing, Dong, Qirong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8258469/
https://www.ncbi.nlm.nih.gov/pubmed/34184072
http://dx.doi.org/10.3892/mmr.2021.12251