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Pharmacokinetics and complementary evaluation system-based guidance on prophylaxis of paediatric patients with haemophilia A in China with Kovaltry: protocol of the LEAP study

INTRODUCTION: Haemophilia A is a rare inherited bleeding disease caused by the deficiency of coagulation factor VIII (FVIII). The main treatment protocol is to administer regular exogenous FVIII concentrate infusions. With the discovery of variability in individualised pharmacokinetics (PK) and blee...

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Detalles Bibliográficos
Autores principales: Kun, Huang, Xu, Weiqun, Zhou, Min, Li, Xiaojing, Xu, Zhongjin, Fang, Yongjun, Li, Changgang, Chen, Zhenping, Wu, Runhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8258559/
https://www.ncbi.nlm.nih.gov/pubmed/34226228
http://dx.doi.org/10.1136/bmjopen-2020-048432