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HSP60-knockdown suppresses proliferation in colorectal cancer cells via activating the adenine/AMPK/mTOR signaling pathway

Colorectal cancer (CRC) is the fourth most lethal cancer in the world. Heat shock protein 60 (HSP60), a mitochondrial chaperone that maintains mitochondrial proteostasis, is highly expressed in tumors compared with in paracancerous tissues, suggesting that high HSP60 expression benefits tumor growth...

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Detalles Bibliográficos
Autores principales: Guo, Jianying, Zhu, Songbiao, Deng, Haiteng, Xu, Renhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8258614/
https://www.ncbi.nlm.nih.gov/pubmed/34267822
http://dx.doi.org/10.3892/ol.2021.12891