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Nox2 impairs VEGF-A-induced angiogenesis in placenta via mitochondrial ROS-STAT3 pathway

Aberrant placental angiogenesis is associated with fetal intrauterine growth restriction (IUGR), but the mechanism underlying abnormal placental angiogenesis remains largely unknown. Here, lower vessel density and higher expression of NADPH oxidases 2 (Nox2) were observed in the placentae for low bi...

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Detalles Bibliográficos
Autores principales: Hu, Chengjun, Wu, Zifang, Huang, Zihao, Hao, Xiangyu, Wang, Shuqi, Deng, Jinping, Yin, Yulong, Tan, Chengquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8258686/
https://www.ncbi.nlm.nih.gov/pubmed/34217063
http://dx.doi.org/10.1016/j.redox.2021.102051