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Nox2 impairs VEGF-A-induced angiogenesis in placenta via mitochondrial ROS-STAT3 pathway
Aberrant placental angiogenesis is associated with fetal intrauterine growth restriction (IUGR), but the mechanism underlying abnormal placental angiogenesis remains largely unknown. Here, lower vessel density and higher expression of NADPH oxidases 2 (Nox2) were observed in the placentae for low bi...
Autores principales: | Hu, Chengjun, Wu, Zifang, Huang, Zihao, Hao, Xiangyu, Wang, Shuqi, Deng, Jinping, Yin, Yulong, Tan, Chengquan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8258686/ https://www.ncbi.nlm.nih.gov/pubmed/34217063 http://dx.doi.org/10.1016/j.redox.2021.102051 |
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