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Role of inner mitochondrial protein OPA1 in mitochondrial dysfunction by tobacco smoking and in the pathogenesis of COPD

BACKGROUND: Chronic lung diseases, such as chronic obstructive pulmonary disease (COPD) and idiopathic pulmonary fibrosis (IPF) are linked to several mitochondrial alterations. Cigarette smoke (CS) alters the structure and function of mitochondria. OPA1 is the main inner mitochondrial GTPase respons...

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Detalles Bibliográficos
Autores principales: Maremanda, Krishna Prahlad, Sundar, Isaac Kirubakaran, Rahman, Irfan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8258692/
https://www.ncbi.nlm.nih.gov/pubmed/34214709
http://dx.doi.org/10.1016/j.redox.2021.102055