Understanding APE1 cellular functions by the structural preference of exonuclease activities

Mammalian apurinic/apyrimidinic (AP) endonuclease 1 (APE1) has versatile enzymatic functions, including redox, endonuclease, and exonuclease activities. APE1 is thus broadly associated with pathways in DNA repair, cancer cell growth, and drug resistance. Unlike its AP site-specific endonuclease acti...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Tung-Chang, Guo, Kai-Wei, Chu, Jhih-Wei, Hsiao, Yu-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8258793/
https://www.ncbi.nlm.nih.gov/pubmed/34285771
http://dx.doi.org/10.1016/j.csbj.2021.06.036

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8258793/
https://www.ncbi.nlm.nih.gov/pubmed/34285771
http://dx.doi.org/10.1016/j.csbj.2021.06.036

Ejemplares similares