Nuclear Transglutaminase 2 interacts with topoisomerase II⍺ to promote DNA damage repair in lung cancer cells

BACKGROUND: To block repairs of DNA damages, especially the DNA double strand break (DSB) repair, can be used to induce cancer cell death. DSB repair depends on a sequential activation of DNA repair factors that may be potentially targeted for clinical cancer therapy. Up to now, many protein compone...

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Detalles Bibliográficos
Autores principales: Lei, Xiao, Cao, Kun, Chen, Yuanyuan, Shen, Hui, Liu, Zhe, Qin, Hongran, Cai, Jianming, Gao, Fu, Yang, Yanyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8258933/
https://www.ncbi.nlm.nih.gov/pubmed/34225780
http://dx.doi.org/10.1186/s13046-021-02009-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8258933/
https://www.ncbi.nlm.nih.gov/pubmed/34225780
http://dx.doi.org/10.1186/s13046-021-02009-2

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