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Wdpcp regulates cellular proliferation and differentiation in the developing limb via hedgehog signaling

BACKGROUND: Mice with a loss of function mutation in Wdpcp were described previously to display severe birth defects in the developing heart, neural tube, and limb buds. Further characterization of the skeletal phenotype of Wdpcp null mice was limited by perinatal lethality. RESULTS: We utilized Prx...

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Detalles Bibliográficos
Autores principales: Langhans, Mark T., Gao, Jingtao, Tang, Ying, Wang, Bing, Alexander, Peter, Tuan, Rocky S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8258940/
https://www.ncbi.nlm.nih.gov/pubmed/34225660
http://dx.doi.org/10.1186/s12861-021-00241-9