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Wdpcp regulates cellular proliferation and differentiation in the developing limb via hedgehog signaling
BACKGROUND: Mice with a loss of function mutation in Wdpcp were described previously to display severe birth defects in the developing heart, neural tube, and limb buds. Further characterization of the skeletal phenotype of Wdpcp null mice was limited by perinatal lethality. RESULTS: We utilized Prx...
Autores principales: | Langhans, Mark T., Gao, Jingtao, Tang, Ying, Wang, Bing, Alexander, Peter, Tuan, Rocky S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8258940/ https://www.ncbi.nlm.nih.gov/pubmed/34225660 http://dx.doi.org/10.1186/s12861-021-00241-9 |
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