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The miR-200–Zeb1 axis regulates key aspects of β-cell function and survival in vivo

OBJECTIVE: The miR-200–Zeb1 axis regulates the epithelial-to-mesenchymal transition (EMT), differentiation, and resistance to apoptosis. A better understanding of these processes in diabetes is highly relevant, as β-cell dedifferentiation and apoptosis contribute to the loss of functional β-cell mas...

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Detalles Bibliográficos
Autores principales: Title, Alexandra C., Silva, Pamuditha N., Godbersen, Svenja, Hasenöhrl, Lynn, Stoffel, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8258987/
https://www.ncbi.nlm.nih.gov/pubmed/34116231
http://dx.doi.org/10.1016/j.molmet.2021.101267