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The miR-200–Zeb1 axis regulates key aspects of β-cell function and survival in vivo
OBJECTIVE: The miR-200–Zeb1 axis regulates the epithelial-to-mesenchymal transition (EMT), differentiation, and resistance to apoptosis. A better understanding of these processes in diabetes is highly relevant, as β-cell dedifferentiation and apoptosis contribute to the loss of functional β-cell mas...
Autores principales: | Title, Alexandra C., Silva, Pamuditha N., Godbersen, Svenja, Hasenöhrl, Lynn, Stoffel, Markus |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8258987/ https://www.ncbi.nlm.nih.gov/pubmed/34116231 http://dx.doi.org/10.1016/j.molmet.2021.101267 |
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