Cargando…

Synaptojanin1 deficiency upregulates basal autophagosome formation in astrocytes

Macroautophagy dysregulation is implicated in multiple neurological disorders, such as Parkinson's disease. While autophagy pathways are heavily researched in heterologous cells and neurons, regulation of autophagy in the astrocyte, the most abundant cell type in the mammalian brain, is less we...

Descripción completa

Detalles Bibliográficos
Autores principales: Pan, Ping-Yue, Zhu, Justin, Rizvi, Asma, Zhu, Xinyu, Tanaka, Hikari, Dreyfus, Cheryl F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8258991/
https://www.ncbi.nlm.nih.gov/pubmed/34126070
http://dx.doi.org/10.1016/j.jbc.2021.100873