Coordinated changes in gene expression kinetics underlie both mouse and human erythroid maturation

BACKGROUND: Single-cell technologies are transforming biomedical research, including the recent demonstration that unspliced pre-mRNA present in single-cell RNA-Seq permits prediction of future expression states. Here we apply this RNA velocity concept to an extended timecourse dataset covering mous...

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Detalles Bibliográficos
Autores principales: Barile, Melania, Imaz-Rosshandler, Ivan, Inzani, Isabella, Ghazanfar, Shila, Nichols, Jennifer, Marioni, John C., Guibentif, Carolina, Göttgens, Berthold
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8258993/
https://www.ncbi.nlm.nih.gov/pubmed/34225769
http://dx.doi.org/10.1186/s13059-021-02414-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8258993/
https://www.ncbi.nlm.nih.gov/pubmed/34225769
http://dx.doi.org/10.1186/s13059-021-02414-y

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