Cargando…

Amiloride ameliorates muscle wasting in cancer cachexia through inhibiting tumor-derived exosome release

BACKGROUND: Cancer cachexia (CAC) reduces patient survival and quality of life. Developments of efficient therapeutic strategies are required for the CAC treatments. This long-term process could be shortened by the drug-repositioning approach which exploits old drugs approved for non-cachexia diseas...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhou, Lin, Zhang, Tong, Shao, Wei, Lu, Ruohan, Wang, Lin, Liu, Haisheng, Jiang, Bin, Li, Shiqin, Zhuo, Huiqin, Wang, Suheng, Li, Qinxi, Huang, Caihua, Lin, Donghai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8258996/
https://www.ncbi.nlm.nih.gov/pubmed/34229732
http://dx.doi.org/10.1186/s13395-021-00274-5