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Amiloride ameliorates muscle wasting in cancer cachexia through inhibiting tumor-derived exosome release
BACKGROUND: Cancer cachexia (CAC) reduces patient survival and quality of life. Developments of efficient therapeutic strategies are required for the CAC treatments. This long-term process could be shortened by the drug-repositioning approach which exploits old drugs approved for non-cachexia diseas...
Autores principales: | Zhou, Lin, Zhang, Tong, Shao, Wei, Lu, Ruohan, Wang, Lin, Liu, Haisheng, Jiang, Bin, Li, Shiqin, Zhuo, Huiqin, Wang, Suheng, Li, Qinxi, Huang, Caihua, Lin, Donghai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8258996/ https://www.ncbi.nlm.nih.gov/pubmed/34229732 http://dx.doi.org/10.1186/s13395-021-00274-5 |
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