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In vivo two-photon microscopy protocol for imaging microglial responses and spine elimination at sites of fibrinogen deposition in mouse brain

Deposition of the blood coagulation factor fibrinogen in the central nervous system is a hallmark of neurological diseases with blood-brain barrier disruption. We describe in vivo two-photon imaging of microglial responses and neuronal spine elimination to either intracortical microinjection of fibr...

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Detalles Bibliográficos
Autores principales: Tognatta, Reshmi, Merlini, Mario, Yan, Zhaoqi, Schuck, Renaud, Davalos, Dimitrios, Akassoglou, Katerina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8259313/
https://www.ncbi.nlm.nih.gov/pubmed/34258598
http://dx.doi.org/10.1016/j.xpro.2021.100638