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Phase separation of YAP reorganizes genome topology for long-term YAP target gene expression
Yes-associated Protein (YAP) is a transcriptional co-activator that regulates cell proliferation and survival by binding to a select set of enhancers for target gene activation. How YAP coordinates these transcriptional responses is unknown. Here, we demonstrate that YAP forms liquid-like condensate...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8259329/ https://www.ncbi.nlm.nih.gov/pubmed/31792379 http://dx.doi.org/10.1038/s41556-019-0433-z |