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Validity of observational evidence on putative risk and protective factors: appraisal of 3744 meta-analyses on 57 topics

BACKGROUND: The validity of observational studies and their meta-analyses is contested. Here, we aimed to appraise thousands of meta-analyses of observational studies using a pre-specified set of quantitative criteria that assess the significance, amount, consistency, and bias of the evidence. We al...

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Detalles Bibliográficos
Autores principales: Janiaud, Perrine, Agarwal, Arnav, Tzoulaki, Ioanna, Theodoratou, Evropi, Tsilidis, Konstantinos K., Evangelou, Evangelos, Ioannidis, John P. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8259334/
https://www.ncbi.nlm.nih.gov/pubmed/34225716
http://dx.doi.org/10.1186/s12916-021-02020-6