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Validity of observational evidence on putative risk and protective factors: appraisal of 3744 meta-analyses on 57 topics
BACKGROUND: The validity of observational studies and their meta-analyses is contested. Here, we aimed to appraise thousands of meta-analyses of observational studies using a pre-specified set of quantitative criteria that assess the significance, amount, consistency, and bias of the evidence. We al...
Autores principales: | Janiaud, Perrine, Agarwal, Arnav, Tzoulaki, Ioanna, Theodoratou, Evropi, Tsilidis, Konstantinos K., Evangelou, Evangelos, Ioannidis, John P. A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8259334/ https://www.ncbi.nlm.nih.gov/pubmed/34225716 http://dx.doi.org/10.1186/s12916-021-02020-6 |
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