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Nampt controls skeletal muscle development by maintaining Ca(2+) homeostasis and mitochondrial integrity
OBJECTIVE: NAD(+) is a co-factor and substrate for enzymes maintaining energy homeostasis. Nicotinamide phosphoribosyltransferase (NAMPT) controls NAD(+) synthesis, and in skeletal muscle, NAD(+) is essential for muscle integrity. However, the underlying molecular mechanisms by which NAD(+) synthesi...
Autores principales: | , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8259345/ https://www.ncbi.nlm.nih.gov/pubmed/34119711 http://dx.doi.org/10.1016/j.molmet.2021.101271 |