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Nampt controls skeletal muscle development by maintaining Ca(2+) homeostasis and mitochondrial integrity

OBJECTIVE: NAD(+) is a co-factor and substrate for enzymes maintaining energy homeostasis. Nicotinamide phosphoribosyltransferase (NAMPT) controls NAD(+) synthesis, and in skeletal muscle, NAD(+) is essential for muscle integrity. However, the underlying molecular mechanisms by which NAD(+) synthesi...

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Detalles Bibliográficos
Autores principales: Basse, Astrid L., Agerholm, Marianne, Farup, Jean, Dalbram, Emilie, Nielsen, Joachim, Ørtenblad, Niels, Altıntaş, Ali, Ehrlich, Amy M., Krag, Thomas, Bruzzone, Santina, Dall, Morten, de Guia, Roldan M., Jensen, Jonas B., Møller, Andreas B., Karlsen, Anders, Kjær, Michael, Barrès, Romain, Vissing, John, Larsen, Steen, Jessen, Niels, Treebak, Jonas T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8259345/
https://www.ncbi.nlm.nih.gov/pubmed/34119711
http://dx.doi.org/10.1016/j.molmet.2021.101271