Distinguishing linear and branched evolution given single-cell DNA sequencing data of tumors

BACKGROUND: Cancer arises from an evolutionary process where somatic mutations give rise to clonal expansions. Reconstructing this evolutionary process is useful for treatment decision-making as well as understanding evolutionary patterns across patients and cancer types. In particular, classifying...

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Detalles Bibliográficos
Autores principales: Weber, Leah L., El-Kebir, Mohammed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8259357/
https://www.ncbi.nlm.nih.gov/pubmed/34229713
http://dx.doi.org/10.1186/s13015-021-00194-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8259357/
https://www.ncbi.nlm.nih.gov/pubmed/34229713
http://dx.doi.org/10.1186/s13015-021-00194-5

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