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Distinguishing linear and branched evolution given single-cell DNA sequencing data of tumors
BACKGROUND: Cancer arises from an evolutionary process where somatic mutations give rise to clonal expansions. Reconstructing this evolutionary process is useful for treatment decision-making as well as understanding evolutionary patterns across patients and cancer types. In particular, classifying...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8259357/ https://www.ncbi.nlm.nih.gov/pubmed/34229713 http://dx.doi.org/10.1186/s13015-021-00194-5 |