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The host transcriptional response to Candidemia is dominated by neutrophil activation and heme biosynthesis and supports novel diagnostic approaches

BACKGROUND: Candidemia is one of the most common nosocomial bloodstream infections in the United States, causing significant morbidity and mortality in hospitalized patients, but the breadth of the host response to Candida infections in human patients remains poorly defined. METHODS: In order to bet...

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Detalles Bibliográficos
Autores principales: Steinbrink, Julie M., Myers, Rachel A., Hua, Kaiyuan, Johnson, Melissa D., Seidelman, Jessica L., Tsalik, Ephraim L., Henao, Ricardo, Ginsburg, Geoffrey S., Woods, Christopher W., Alexander, Barbara D., McClain, Micah T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8259367/
https://www.ncbi.nlm.nih.gov/pubmed/34225776
http://dx.doi.org/10.1186/s13073-021-00924-9