CCND1 copy number increase and cyclin D1 expression in acral melanoma: a comparative study of fluorescence in situ hybridization and immunohistochemistry in a Chinese cohort

BACKGROUND: CCND1 copy number increase is characteristic of acral melanoma and is useful in distinguishing benign and malignant acral melanocytic lesions. Increase of the gene copy number may result in protein overexpression. This raises the possibility that detection of high expression of cyclin D1...

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Detalles Bibliográficos
Autores principales: Liu, Jianying, Yu, Wenjuan, Gao, Fei, Qi, Shuangshuang, Du, Juan, Ma, Xiaolong, Zhang, Yan, Zheng, Jie, Su, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8259423/
https://www.ncbi.nlm.nih.gov/pubmed/34225728
http://dx.doi.org/10.1186/s13000-021-01116-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8259423/
https://www.ncbi.nlm.nih.gov/pubmed/34225728
http://dx.doi.org/10.1186/s13000-021-01116-0

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