Origin of complexity in hemoglobin evolution

Most proteins associate into multimeric complexes with specific architectures(1,2), which often have functional properties like cooperative ligand binding or allosteric regulation(3). No detailed knowledge is available about how any multimer and its functions arose during historical evolution. Here...

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Detalles Bibliográficos
Autores principales: Pillai, Arvind S., Chandler, Shane A., Liu, Yang, Signore, Anthony V., Cortez-Romero, Carlos R., Benesch, Justin L.P., Laganowsky, Arthur, Storz, Jay F., Hochberg, Georg K.A., Thornton, Joseph W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8259614/
https://www.ncbi.nlm.nih.gov/pubmed/32461643
http://dx.doi.org/10.1038/s41586-020-2292-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8259614/
https://www.ncbi.nlm.nih.gov/pubmed/32461643
http://dx.doi.org/10.1038/s41586-020-2292-y

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