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Origin of complexity in hemoglobin evolution
Most proteins associate into multimeric complexes with specific architectures(1,2), which often have functional properties like cooperative ligand binding or allosteric regulation(3). No detailed knowledge is available about how any multimer and its functions arose during historical evolution. Here...
Autores principales: | Pillai, Arvind S., Chandler, Shane A., Liu, Yang, Signore, Anthony V., Cortez-Romero, Carlos R., Benesch, Justin L.P., Laganowsky, Arthur, Storz, Jay F., Hochberg, Georg K.A., Thornton, Joseph W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8259614/ https://www.ncbi.nlm.nih.gov/pubmed/32461643 http://dx.doi.org/10.1038/s41586-020-2292-y |
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