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Upregulation of brain hepcidin in prion diseases: Short title: Hepcidin and brain iron accumulation

Accumulation of redox-active iron in human sporadic Creutzfeldt-Jakob disease (sCJD) brain tissue and scrapie-infected mouse brains has been demonstrated previously. Here, we explored whether upregulation of local hepcidin secreted within the brain is the underlying cause of iron accumulation and as...

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Detalles Bibliográficos
Autores principales: Chaudhary, Suman, Ashok, Ajay, Wise, Aaron S., Rana, Neil A., McDonald, Dallas, Kritikos, Alexander E., Kong, Qingzhong, Singh, Neena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8259718/
https://www.ncbi.nlm.nih.gov/pubmed/34224321
http://dx.doi.org/10.1080/19336896.2021.1946377