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Upregulation of brain hepcidin in prion diseases: Short title: Hepcidin and brain iron accumulation
Accumulation of redox-active iron in human sporadic Creutzfeldt-Jakob disease (sCJD) brain tissue and scrapie-infected mouse brains has been demonstrated previously. Here, we explored whether upregulation of local hepcidin secreted within the brain is the underlying cause of iron accumulation and as...
Autores principales: | Chaudhary, Suman, Ashok, Ajay, Wise, Aaron S., Rana, Neil A., McDonald, Dallas, Kritikos, Alexander E., Kong, Qingzhong, Singh, Neena |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8259718/ https://www.ncbi.nlm.nih.gov/pubmed/34224321 http://dx.doi.org/10.1080/19336896.2021.1946377 |
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