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Baicalein inhibits the pharmacokinetics of simvastatin in rats via regulating the activity of CYP3A4

CONTEXT: Baicalein and simvastatin possess similar pharmacological activities and indications. The risk of their co-administration was unclear. OBJECTIVE: The interaction between baicalein and simvastatin was investigated to provide reference and guidance for the clinical application of the combinat...

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Detalles Bibliográficos
Autores principales: Meng, Meng, Li, Xin, Zhang, Xiuwen, Sun, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8259816/
https://www.ncbi.nlm.nih.gov/pubmed/34214011
http://dx.doi.org/10.1080/13880209.2021.1942927