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Baicalein inhibits the pharmacokinetics of simvastatin in rats via regulating the activity of CYP3A4

CONTEXT: Baicalein and simvastatin possess similar pharmacological activities and indications. The risk of their co-administration was unclear. OBJECTIVE: The interaction between baicalein and simvastatin was investigated to provide reference and guidance for the clinical application of the combinat...

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Detalles Bibliográficos
Autores principales:	Meng, Meng, Li, Xin, Zhang, Xiuwen, Sun, Bin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8259816/ https://www.ncbi.nlm.nih.gov/pubmed/34214011 http://dx.doi.org/10.1080/13880209.2021.1942927

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