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PTPRM methylation induced by FN1 promotes the development of glioblastoma by activating STAT3 signalling

CONTEXT: The phosphorylation of signal transducer and activator of transcription protein 3 (STAT3) is up-regulated in glioblastoma (GBM) cells and is regulated by protein tyrosine phosphatase receptor type M (PTPRM). Fibronectin-1 (FN1) is also reported to be up-regulated in GBM. OBJECTIVE: We explo...

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Detalles Bibliográficos
Autores principales: Song, Jian, Zhao, Di, Sun, Guozhu, Yang, Jiankai, Lv, Zhongqiang, Jiao, Baohua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8259858/
https://www.ncbi.nlm.nih.gov/pubmed/34225581
http://dx.doi.org/10.1080/13880209.2021.1944220