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PTPRM methylation induced by FN1 promotes the development of glioblastoma by activating STAT3 signalling
CONTEXT: The phosphorylation of signal transducer and activator of transcription protein 3 (STAT3) is up-regulated in glioblastoma (GBM) cells and is regulated by protein tyrosine phosphatase receptor type M (PTPRM). Fibronectin-1 (FN1) is also reported to be up-regulated in GBM. OBJECTIVE: We explo...
Autores principales: | Song, Jian, Zhao, Di, Sun, Guozhu, Yang, Jiankai, Lv, Zhongqiang, Jiao, Baohua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8259858/ https://www.ncbi.nlm.nih.gov/pubmed/34225581 http://dx.doi.org/10.1080/13880209.2021.1944220 |
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