Design and green synthesis of novel quinolinone derivatives of potential anti-breast cancer activity against MCF-7 cell line targeting multi-receptor tyrosine kinases

A new set of 4,6,7,8-tetrahydroquinolin-5(1H)-ones were designed as cytotoxic agents against breast cancer cell line (MCF-7) and synthesised under ultrasonic irradiation using chitosan decorated copper nanoparticles (CS/CuNPs) catalyst. The new compounds 4b, 4j, 4k, and 4e exhibited the most potent...

Descripción completa

Detalles Bibliográficos
Autores principales: Mokhtar, Mohamed, Alghamdi, Khadijah S., Ahmed, Nesreen S., Bakhotmah, Dina, Saleh, Tamer S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8259865/
https://www.ncbi.nlm.nih.gov/pubmed/34210212
http://dx.doi.org/10.1080/14756366.2021.1944126

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8259865/
https://www.ncbi.nlm.nih.gov/pubmed/34210212
http://dx.doi.org/10.1080/14756366.2021.1944126

Ejemplares similares