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Novel aspects of iron homeostasis in pathogenic bloodstream form Trypanosoma brucei

Iron is an essential regulatory signal for virulence factors in many pathogens. Mammals and bloodstream form (BSF) Trypanosoma brucei obtain iron by receptor-mediated endocytosis of transferrin bound to receptors (TfR) but the mechanisms by which T. brucei subsequently handles iron remains enigmatic...

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Detalles Bibliográficos
Autores principales: Gilabert Carbajo, Carla, Cornell, Lucy J., Madbouly, Youssef, Lai, Zhihao, Yates, Phillip A., Tinti, Michele, Tiengwe, Calvin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8259959/
https://www.ncbi.nlm.nih.gov/pubmed/34161395
http://dx.doi.org/10.1371/journal.ppat.1009696