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Novel aspects of iron homeostasis in pathogenic bloodstream form Trypanosoma brucei
Iron is an essential regulatory signal for virulence factors in many pathogens. Mammals and bloodstream form (BSF) Trypanosoma brucei obtain iron by receptor-mediated endocytosis of transferrin bound to receptors (TfR) but the mechanisms by which T. brucei subsequently handles iron remains enigmatic...
Autores principales: | Gilabert Carbajo, Carla, Cornell, Lucy J., Madbouly, Youssef, Lai, Zhihao, Yates, Phillip A., Tinti, Michele, Tiengwe, Calvin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8259959/ https://www.ncbi.nlm.nih.gov/pubmed/34161395 http://dx.doi.org/10.1371/journal.ppat.1009696 |
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