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Detection of significant antiviral drug effects on COVID-19 with reasonable sample sizes in randomized controlled trials: A modeling study

BACKGROUND: Development of an effective antiviral drug for Coronavirus Disease 2019 (COVID-19) is a global health priority. Although several candidate drugs have been identified through in vitro and in vivo models, consistent and compelling evidence from clinical studies is limited. The lack of evid...

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Detalles Bibliográficos
Autores principales: Iwanami, Shoya, Ejima, Keisuke, Kim, Kwang Su, Noshita, Koji, Fujita, Yasuhisa, Miyazaki, Taiga, Kohno, Shigeru, Miyazaki, Yoshitsugu, Morimoto, Shimpei, Nakaoka, Shinji, Koizumi, Yoshiki, Asai, Yusuke, Aihara, Kazuyuki, Watashi, Koichi, Thompson, Robin N., Shibuya, Kenji, Fujiu, Katsuhito, Perelson, Alan S., Iwami, Shingo, Wakita, Takaji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8259968/
https://www.ncbi.nlm.nih.gov/pubmed/34228712
http://dx.doi.org/10.1371/journal.pmed.1003660